NILM techniques for intelligent home energy management and ambient assisted living: a review

The ongoing deployment of smart meters and different commercial devices has made electricity disaggregation feasible in buildings and households, based on a single measure of the current and, sometimes, of the voltage. Energy disaggregation is intended to separate the total power consumption into specific appliance loads, which can be achieved by applying Non-Intrusive Load Monitoring (NILM) techniques with a minimum invasion of privacy. NILM techniques are becoming more and more widespread in recent years, as a consequence of the interest companies and consumers have in efficient energy consumption and management. This work presents a detailed review of NILM methods, focusing particularly on recent proposals and their applications, particularly in the areas of Home Energy Management Systems (HEMS) and Ambient Assisted Living (AAL), where the ability to determine the on/off status of certain devices can provide key information for making further decisions. As well as complementing previous reviews on the NILM field and providing a discussion of the applications of NILM in HEMS and AAL, this paper provides guidelines for future research in these topics.Agência financiadora: Programa Operacional Portugal 2020 and Programa Operacional Regional do Algarve 01/SAICT/2018/39578 Fundação para a Ciência e Tecnologia through IDMEC, under LAETA: SFRH/BSAB/142998/2018 SFRH/BSAB/142997/2018 UID/EMS/50022/2019 Junta de Comunidades de Castilla-La-Mancha, Spain: SBPLY/17/180501/000392 Spanish Ministry of Economy, Industry and Competitiveness (SOC-PLC project): TEC2015-64835-C3-2-R MINECO/FEDERinfo:eu-repo/semantics/publishedVersio

Agencia para el Desarrollo Económico de Pérez Zeledón (APDPZ), Costa Rica: Diseño de una Estructura para la Promoción de Emprendimientos en el ámbito de la economía social (EPES)

El Proyecto Zona Económica Especial de Pérez Zeledón, en Costa Rica, tiene entre sus objetivos la promoción, en este Cantón, de una zona para el desarrollo socioeconómico y la creación de fuentes de empleo de calidad, propiciando el mejoramiento de las condiciones de vida de sus habitantes, la mejora de la competitividad, el aumento de las exportaciones y la promoción de emprendimientos y de pequeñas y medianas empresas en el cantón de Pérez Zeledón. La creación de la Zona Económica Especial, en agosto de 2016, mediante el Decreto Ejecutivo n º 39876-MEIC-COMEX-MTSS, confiere a la Agencia para el Desarrollo de Pérez Zeledón (APDPZ) la responsabilidad de su implementación. El objetivo general del presente trabajo final de maestría (TFM) es diseñar una estructura específica de la APDPZ, para la Promoción de Emprendimientos en el ámbito de la economía social (EPES), que se designarán en el trabajo como “emprendimientos sociales”. Para llevar adelante el proceso se hace necesario contar con una metodología de trabajo que permita a los diversos actores acceder a alternativas de financiamiento y asistencia técnica para el desarrollo de sus negocios. Se propone, por tanto, a partir del Plan estratégico de la APDPZ, un proyecto para promover y fortalecer emprendimientos sociales que viabilicen la incorporación de valor social y económico agregado, a través de la comercialización nacional e internacional de productos y servicios generados en la comunidad, así como la atención de áreas estratégicas como seguridad alimentaria, agroindustria, turismo y tecnología. El modelo propuesto procura dotar a la Agencia para el Desarrollo de Pérez Zeledón de un mecanismo para orientar las acciones de los diversos actores sociales y económicos que es necesario vincular para la promoción y fortalecimiento de emprendimientos sociales surgidos a partir de los propios interesados, como producto del esfuerzo articulado de la APDPZ para generar acciones que conduzcan al cumplimiento de los objetivos con dan origen a su creación.O Projeto Zona Económica Especial Pérez Zeledón, na Costa Rica, tem entre seus objetivos a promoção, neste cantão, de uma área de desenvolvimento socioeconômico e a criação de fontes de emprego de qualidade, promovendo a melhoria das condições de vida de seus habitantes, a melhoria da competitividade, o aumento das exportações e a promoção do empreendedorismo e das pequenas e médias empresas no cantão de Pérez Zeledón. A criação da Zona Econômica Especial, em agosto de 2016, por meio do Decreto Executivo nº 39.876-MEIC-COMEX-MTSS, atribuiu a responsabilidade de sua implementação à Agência de Desenvolvimento Pérez Zeledón (APDPZ). O objetivo geral deste projeto final de mestrado (TFM) é conceber uma estrutura específica da APDPZ, para a Promoção do Empreendedorismo no domínio da economia social (EPES), que será designada no trabalho como “empreendedorismo social”. Para realizar o processo, é necessário ter uma metodologia de trabalho que permita aos diversos atores acessar alternativas de financiamento e assistência técnica para o desenvolvimento de seus negócios. Assim, com base no Plano Estratégico da APDPZ, propõe-se um projeto de promoção e fortalecimento de empreendimentos sociais que possibilitem a incorporação de valor social e econômico agregado, por meio da comercialização nacional e internacional de produtos e serviços gerados na comunidade. como atenção a áreas estratégicas como segurança alimentar, agronegócio, turismo e tecnologia. O modelo proposto busca dotar a Agência de Desenvolvimento Pérez Zeledón de um mecanismo para orientar as ações dos diversos atores sociais e econômicos que é necessário vincular para a promoção e fortalecimento de empreendimentos sociais surgidos das próprias partes interessadas, como produto de o esforço articulado da APDPZ para gerar ações que levem ao cumprimento dos objetivos que deram origem à sua criação.The Pérez Zeledón Special Economic Zone Project, in Costa Rica, has among its objectives the promotion, in this Canton, of an area for socioeconomic development and the creation of quality employment sources, promoting the improvement of the living conditions of its inhabitants, the improvement of competitiveness, the increase in exports and the promotion of entrepreneurship and small and medium-sized enterprises in the canton of Pérez Zeledón. The creation of the Special Economic Zone, in August 2016, through Executive Decree No. 39876-MEIC-COMEX-MTSS, conferred responsibility for its implementation on the Pérez Zeledón Development Agency (APDPZ). The general objective of this final master's project (TFM) is to design a specific structure of the APDPZ, for the Promotion of Entrepreneurship in the field of social economy (EPES), which will be designated in the work as "social entrepreneurship". To carry out the process, it is necessary to have a work methodology that allows the various actors to access financing alternatives and technical assistance for the development of their businesses. Therefore, based on the Strategic Plan of the APDPZ, a project is proposed to promote and strengthen social enterprises that enable the incorporation of added social and economic value, through the national and international marketing of products and services generated in the community. , as well as attention to strategic areas such as food security, agribusiness, tourism and technology. The proposed model seeks to provide the Pérez Zeledón Development Agency with a mechanism to guide the actions of the various social and economic actors that it is necessary to link for the promotion and strengthening of social enterprises arising from the interested parties themselves, as a product of the articulated effort of the APDPZ to generate actions that lead to the fulfillment of the objectives that gave rise to its creation

Nuevo método de análisis de elementos químicos, metales y no metales en líquidos por ablación láser previa congelación de la muestra

Depto. de Química AnalíticaFac. de Ciencias Químicaspu

The Cross Talk between Underlying Mechanisms of Multiple Sclerosis and Epilepsy May Provide New Insights for More Efficient Therapies

Despite the significant differences in pathological background of neurodegenerative diseases, epileptic seizures are a comorbidity in many disorders such as Huntington disease (HD), Alzheimer’s disease (AD), and multiple sclerosis (MS). Regarding the last one, specifically, it has been shown that the risk of developing epilepsy is three to six times higher in patients with MS compared to the general population. In this context, understanding the pathological processes underlying this connection will allow for the targeting of the common and shared pathological pathways involved in both conditions, which may provide a new avenue in the management of neurological disorders. This review provides an outlook of what is known so far about the bidirectional association between epilepsy and MS

Treatment of Donor Rat Hearts Prior to Transplantation with FLIP (FADD-Like Interleukin Beta-Converting Enzyme (FLICE)-Like Inhibitory Protein) in Cardioplegic Solution Decreased Apoptosis at Thirty Minutes Post-transplantation and Decreased Total Tyrosine Phosphorylation Levels

BACKGROUND Heart transplantation is a therapeutic option for patients with severe coronary artery disease or heart failure. One of the difficulties to overcome is the apoptosis of cardiomyocytes in the donor organ. To prevent apoptosis in the donor organ, we developed a fusion protein containing FLIP (FADD-like interleukin beta-converting enzyme (FLICE)-like inhibitory protein) to inhibit caspase-8. MATERIAL AND METHODS We linked the cDNA coding for the FLIP protein to the transduction domain of HIV (human immunodeficiency virus) to allow the protein to enter cells. The recombinant protein was used at two different concentrations, 3 nM and 30 nM, for treatment of the donor heart in rat transplantation experiments. After transplantation, apoptosis was measured by ELISA, and the levels of active caspase-3, caspase-8, Bid, and PUMA were determined by western blotting using specific antibodies. RESULTS We observed that treatment of the donor organ with a solution containing this protein reduced the apoptosis level in the donor organ after 30 minutes post-transplantation as measured by the total of apoptotic cells with ELISA assay, and caspase-8 and caspase-3 activation and decreased levels of BH3-only proteins such as Bid and PUMA. Furthermore, this treatment also reduced the total tyrosine phosphorylation levels, which may be a possible measurement of lower oxidative stress levels in cardiomyocytes. CONCLUSIONS Protein FLIP solution reduced apoptosis at 30 minutes post-transplantation and decreased levels of several regulators of apoptosis

Doppler-tolerant receiver for an ultrasonic LPS based on Kasami sequences

This paper presents the design of a novel receiver for a broadband ultrasonic Local Positioning System. As other devices based on matched ltering of the transmitted encoded signals, this receiver features high robustness to noise and multiple access capability. Unlike these previous solutions, the proposed receiver is capable to detect the beacons emissions despite being installed in a fast moving user and to provide an estimation of its velocity. This system has been implemented on a FPGA based architecture. An experimental analysis of the sensor performance has been carried out with a set of test signals synthetically generated to simulate diferent positions and velocities for this receiver. The results confirm the capability of the system to detect the encoded signals emitted by the LPS architecture when moving at velocities of up to 3 m/s under low SNR conditions.Fil: Alvarez, Fernando J.. Universidad de Extremadura; EspañaFil: Hernadez, Alvaro. Universidad de Alcala; EspañaFil: Moreno, José A.. Universidad de Extremadura; EspañaFil: Perez, M. Carmen. Universidad de Alcala; EspañaFil: Ureña, Jesus. Universidad de Alcala; EspañaFil: de Marziani, Carlos Manuel. Universidad Nacional de la Patagonia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; Argentin